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Single molecule linear analysis of DNA in nano-channel labeled with sequence specific fluorescent probes
An array of nano-channels was fabricated from silicon based semiconductor materials to stretch long, native dsDNA. Here we present a labeling scheme in which it is possible to identify the location of specific sequences along the stretched DNA molecules. The scheme proceeds by first using the strand...
| Autores principales: | , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2010
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2952877/ https://www.ncbi.nlm.nih.gov/pubmed/20699272 http://dx.doi.org/10.1093/nar/gkq673 |