12/15-Lipoxygenase Is an Interleukin-13 and Interferon-γ Counterregulated-Mediator of Allergic Airway Inflammation

Interleukin-13 and interferon-γ are important effectors of T-helper cells. Interleukin-13 increases expression of the arachidonic acid-metabolizing enzyme, 15-lipoxygenase-1, in a variety of cell types. 15-lipoxygenase-1 is dramatically elevated in the airways of subjects with asthma. Studies in ani...

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Detalles Bibliográficos
Autores principales: Lindley, Alexa R., Crapster-Pregont, Margaret, Liu, Yanjun, Kuperman, Douglas A.
Formato: Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2952968/
https://www.ncbi.nlm.nih.gov/pubmed/20953328
http://dx.doi.org/10.1155/2010/727305

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2952968/
https://www.ncbi.nlm.nih.gov/pubmed/20953328
http://dx.doi.org/10.1155/2010/727305

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