The differential interaction of snRNPs with pre-mRNA reveals splicing kinetics in living cells

Precursor messenger RNA (pre-mRNA) splicing is catalyzed by the spliceosome, a large ribonucleoprotein (RNP) complex composed of five small nuclear RNP particles (snRNPs) and additional proteins. Using live cell imaging of GFP-tagged snRNP components expressed at endogenous levels, we examined how t...

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Detalles Bibliográficos
Autores principales: Huranová, Martina, Ivani, Ivan, Benda, Aleš, Poser, Ina, Brody, Yehuda, Hof, Martin, Shav-Tal, Yaron, Neugebauer, Karla M., Staněk, David
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2010
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2953428/
https://www.ncbi.nlm.nih.gov/pubmed/20921136
http://dx.doi.org/10.1083/jcb.201004030

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2953428/
https://www.ncbi.nlm.nih.gov/pubmed/20921136
http://dx.doi.org/10.1083/jcb.201004030

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