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Kinesin-1 and dynein at the nuclear envelope mediate the bidirectional migrations of nuclei

Kinesin-1 and dynein are recruited to the nuclear envelope by the Caenorhabditis elegans klarsicht/ANC-1/Syne homology (KASH) protein UNC-83 to move nuclei. The mechanisms of how these motors are coordinated to mediate nuclear migration are unknown. Time-lapse differential interference contrast and...

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Detalles Bibliográficos
Autores principales: Fridolfsson, Heidi N., Starr, Daniel A.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2953438/
https://www.ncbi.nlm.nih.gov/pubmed/20921138
http://dx.doi.org/10.1083/jcb.201004118