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The dynamic interaction of AMBRA1 with the dynein motor complex regulates mammalian autophagy
Autophagy is an evolutionary conserved catabolic process involved in several physiological and pathological processes such as cancer and neurodegeneration. Autophagy initiation signaling requires both the ULK1 kinase and the BECLIN 1–VPS34 core complex to generate autophagosomes, double-membraned ve...
Autores principales: | , , , , , , , , , , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2953445/ https://www.ncbi.nlm.nih.gov/pubmed/20921139 http://dx.doi.org/10.1083/jcb.201002100 |