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The dynamic interaction of AMBRA1 with the dynein motor complex regulates mammalian autophagy

Autophagy is an evolutionary conserved catabolic process involved in several physiological and pathological processes such as cancer and neurodegeneration. Autophagy initiation signaling requires both the ULK1 kinase and the BECLIN 1–VPS34 core complex to generate autophagosomes, double-membraned ve...

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Detalles Bibliográficos
Autores principales: Di Bartolomeo, Sabrina, Corazzari, Marco, Nazio, Francesca, Oliverio, Serafina, Lisi, Gaia, Antonioli, Manuela, Pagliarini, Vittoria, Matteoni, Silvia, Fuoco, Claudia, Giunta, Luigi, D'Amelio, Marcello, Nardacci, Roberta, Romagnoli, Alessandra, Piacentini, Mauro, Cecconi, Francesco, Fimia, Gian Maria
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2953445/
https://www.ncbi.nlm.nih.gov/pubmed/20921139
http://dx.doi.org/10.1083/jcb.201002100

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