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Catalytic Mechanism of Cellulose Degradation by a Cellobiohydrolase, CelS

The hydrolysis of cellulose is the bottleneck in cellulosic ethanol production. The cellobiohydrolase CelS from Clostridium thermocellum catalyzes the hydrolysis of cello-oligosaccharides via inversion of the anomeric carbon. Here, to examine key features of the CelS-catalyzed reaction, QM/MM (SCCDF...

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Detalles Bibliográficos
Autores principales: Saharay, Moumita, Guo, Hong, Smith, Jeremy C.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2953488/
https://www.ncbi.nlm.nih.gov/pubmed/20967294
http://dx.doi.org/10.1371/journal.pone.0012947