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Catalytic Mechanism of Cellulose Degradation by a Cellobiohydrolase, CelS
The hydrolysis of cellulose is the bottleneck in cellulosic ethanol production. The cellobiohydrolase CelS from Clostridium thermocellum catalyzes the hydrolysis of cello-oligosaccharides via inversion of the anomeric carbon. Here, to examine key features of the CelS-catalyzed reaction, QM/MM (SCCDF...
Autores principales: | Saharay, Moumita, Guo, Hong, Smith, Jeremy C. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2953488/ https://www.ncbi.nlm.nih.gov/pubmed/20967294 http://dx.doi.org/10.1371/journal.pone.0012947 |
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