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Profound Depletion of HIV-1 Transcription in Patients Initiating Antiretroviral Therapy during Acute Infection

BACKGROUND: Although combination antiretroviral therapy (cART) initiated in the acute phase of HIV-1 infection may prevent expansion of the latent reservoir, its benefits remain controversial. In the current study, HIV-1 RNA transcription patterns in peripheral blood mononuclear cells (PBMC) were mo...

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Detalles Bibliográficos
Autores principales: Schmid, Adrian, Gianella, Sara, von Wyl, Viktor, Metzner, Karin J., Scherrer, Alexandra U., Niederöst, Barbara, Althaus, Claudia F., Rieder, Philip, Grube, Christina, Joos, Beda, Weber, Rainer, Fischer, Marek, Günthard, Huldrych F.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2953504/
https://www.ncbi.nlm.nih.gov/pubmed/20967271
http://dx.doi.org/10.1371/journal.pone.0013310