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Molecular Immune Responses to Aerosol Challenge with Francisella tularensis in Mice Inoculated with Live Vaccine Candidates of Varying Efficacy

BACKGROUND: Francisella tularensis is a facultative intracellular bacterial pathogen and the etiological agent of tularemia. The subspecies F. tularensis tularensis is especially virulent for humans when inhaled and respiratory tularemia is associated with high mortality if not promptly treated. A l...

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Detalles Bibliográficos
Autores principales: Shen, Hua, Harris, Gregory, Chen, Wangxue, Sjostedt, Anders, Ryden, Patrik, Conlan, Wayne
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2953512/
https://www.ncbi.nlm.nih.gov/pubmed/20967278
http://dx.doi.org/10.1371/journal.pone.0013349