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Molecular Immune Responses to Aerosol Challenge with Francisella tularensis in Mice Inoculated with Live Vaccine Candidates of Varying Efficacy
BACKGROUND: Francisella tularensis is a facultative intracellular bacterial pathogen and the etiological agent of tularemia. The subspecies F. tularensis tularensis is especially virulent for humans when inhaled and respiratory tularemia is associated with high mortality if not promptly treated. A l...
Autores principales: | Shen, Hua, Harris, Gregory, Chen, Wangxue, Sjostedt, Anders, Ryden, Patrik, Conlan, Wayne |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2953512/ https://www.ncbi.nlm.nih.gov/pubmed/20967278 http://dx.doi.org/10.1371/journal.pone.0013349 |
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