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Subtle Alterations in PCNA-Partner Interactions Severely Impair DNA Replication and Repair

The robustness of complex biological processes in the face of environmental and genetic perturbations is a key biological trait. However, while robustness has been extensively studied, little is known regarding the fragility of biological processes. Here, we have examined the susceptibility of DNA r...

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Detalles Bibliográficos
Autores principales: Fridman, Yearit, Palgi, Niv, Dovrat, Daniel, Ben-Aroya, Shay, Hieter, Philip, Aharoni, Amir
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2953525/
https://www.ncbi.nlm.nih.gov/pubmed/20967232
http://dx.doi.org/10.1371/journal.pbio.1000507