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BH3-only protein Bmf mediates apoptosis upon inhibition of CAP-dependent protein synthesis

Tight transcriptional regulation, post-translational modifications and/or alternative splicing of BH3-only proteins fine-tune their pro-apoptotic function. Here, we characterize the gene locus of the BH3-only protein Bmf (Bcl-2 modifying factor) and describe the generation of two major isoforms from...

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Detalles Bibliográficos
Autores principales: Grespi, Francesca, Soratroi, Claudia, Krumschnabel, Gerhard, Sohm, Benedicte, Ploner, Christian, Geley, Stephan, Hengst, Ludger, Häcker, Georg, Villunger, Andreas
Formato: Texto
Lenguaje:English
Publicado: 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2953534/
https://www.ncbi.nlm.nih.gov/pubmed/20706276
http://dx.doi.org/10.1038/cdd.2010.97