Individual and overlapping roles of BH3-only proteins Bim and Bad in apoptosis of lymphocytes and platelets and in suppression of thymic lymphoma development

BH3-only proteins, such as Bim and Bad, contribute to tissue homeostasis by initiating apoptosis in a cell type- and stimulus-specific manner. Loss of Bim provokes lymphocyte accumulation in vivo and renders lymphocytes more resistant to diverse apoptotic stimuli and Bad has been implicated in the a...

Descripción completa

Detalles Bibliográficos
Autores principales: Kelly, PN, White, MJ, Goschnick, MW, Fairfax, KA, Tarlinton, DM, Kinkel, SA, Bouillet, P, Adams, JM, Kile, BT, Strasser, A
Formato: Texto
Lenguaje:English
Publicado: 2010
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2953537/
https://www.ncbi.nlm.nih.gov/pubmed/20431598
http://dx.doi.org/10.1038/cdd.2010.43

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2953537/
https://www.ncbi.nlm.nih.gov/pubmed/20431598
http://dx.doi.org/10.1038/cdd.2010.43

Ejemplares similares