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Tikhonov adaptively regularized gamma variate fitting to assess plasma clearance of inert renal markers

The Tk-GV model fits Gamma Variates (GV) to data by Tikhonov regularization (Tk) with shrinkage constant, λ, chosen to minimize the relative error in plasma clearance, CL (ml/min). Using (169)Yb-DTPA and (99m)Tc-DTPA (n = 46, 8–9 samples, 5–240 min) bolus-dilution curves, results were obtained for f...

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Detalles Bibliográficos
Autores principales: Wesolowski, Carl A., Puetter, Richard C., Ling, Lin, Babyn, Paul S.
Formato: Texto
Lenguaje:English
Publicado: Springer US 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2953622/
https://www.ncbi.nlm.nih.gov/pubmed/20865304
http://dx.doi.org/10.1007/s10928-010-9167-z