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Synthetic associations in the context of genome-wide association scan signals
Genome-wide association studies (GWAS) have successfully identified a large number of genetic variants associated with complex traits, but these only explain a small proportion of the total heritability. It has been recently proposed that rare variants can create ‘synthetic association' signals...
Autores principales: | , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2953742/ https://www.ncbi.nlm.nih.gov/pubmed/20805105 http://dx.doi.org/10.1093/hmg/ddq368 |