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Synthetic associations in the context of genome-wide association scan signals

Genome-wide association studies (GWAS) have successfully identified a large number of genetic variants associated with complex traits, but these only explain a small proportion of the total heritability. It has been recently proposed that rare variants can create ‘synthetic association' signals...

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Detalles Bibliográficos
Autores principales:	Orozco, Gisela, Barrett, Jeffrey C., Zeggini, Eleftheria
Formato:	Texto
Lenguaje:	English
Publicado:	Oxford University Press 2010
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2953742/ https://www.ncbi.nlm.nih.gov/pubmed/20805105 http://dx.doi.org/10.1093/hmg/ddq368

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