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Jagged1 Expression Regulated by Notch3 and Wnt/β-catenin Signaling Pathways in Ovarian Cancer

Ovarian serous carcinoma is a highly aggressive neoplastic disease in women. Our previous studies have demonstrated Notch3 gene amplification and upregulation in many ovarian serous carcinomas and Notch pathway activity contributed to drug resistance. Among different Notch3 ligands, Jagged1 is most...

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Detalles Bibliográficos
Autores principales: Chen, Xu, Stoeck, Alexander, Lee, Soo Jung, Shih, Ie-Ming, Wang, Michael M., Wang, Tian-Li
Formato: Texto
Lenguaje:English
Publicado: Impact Journals LLC 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2953807/
https://www.ncbi.nlm.nih.gov/pubmed/20953350