Muscle-specific inositide phosphatase (MIP/MTMR14) is reduced with age and its loss accelerates skeletal muscle aging process by altering calcium homeostasis

We have recently reported that a novel muscle-specific inositide phosphatase (MIP/MTMR14) plays a critical role in [Ca(2+)](i) homeostasis through dephosphorylation of sn-1-stearoyl-2-arachidonoyl phosphatidylinositol (3,5) bisphosphate (PI(3,5)P2). Loss of function mutations in MIP have been identi...

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Detalles Bibliográficos
Autores principales: Romero-Suarez, Sandra, Shen, Jinhua, Brotto, Leticia, Hall, Todd, Mo, ChengLin, Valdivia, Héctor H., Andresen, Jon, Wacker, Michael, Nosek, Thomas M., Qu, Cheng-Kui, Brotto, Marco
Formato: Texto
Lenguaje:English
Publicado: Impact Journals LLC 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2954041/
https://www.ncbi.nlm.nih.gov/pubmed/20817957

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2954041/
https://www.ncbi.nlm.nih.gov/pubmed/20817957

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