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Muscle-specific inositide phosphatase (MIP/MTMR14) is reduced with age and its loss accelerates skeletal muscle aging process by altering calcium homeostasis
We have recently reported that a novel muscle-specific inositide phosphatase (MIP/MTMR14) plays a critical role in [Ca(2+)](i) homeostasis through dephosphorylation of sn-1-stearoyl-2-arachidonoyl phosphatidylinositol (3,5) bisphosphate (PI(3,5)P2). Loss of function mutations in MIP have been identi...
Autores principales: | Romero-Suarez, Sandra, Shen, Jinhua, Brotto, Leticia, Hall, Todd, Mo, ChengLin, Valdivia, Héctor H., Andresen, Jon, Wacker, Michael, Nosek, Thomas M., Qu, Cheng-Kui, Brotto, Marco |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2954041/ https://www.ncbi.nlm.nih.gov/pubmed/20817957 |
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