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Involvement of p114-RhoGEF and Lfc in Wnt-3a– and Dishevelled-Induced RhoA Activation and Neurite Retraction in N1E-115 Mouse Neuroblastoma Cells

The Wnt-induced planar cell polarity (PCP) signaling pathway is essential for polarized cell migration and morphogenesis. Dishevelled (Dvl) and its binding protein Daam1 mediate RhoA activation in this pathway. WGEF, a member of the Rho-guanine nucleotide exchange factor (Rho-GEF) family, was shown...

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Detalles Bibliográficos
Autores principales: Tsuji, Takuji, Ohta, Yusaku, Kanno, Yuya, Hirose, Kenzo, Ohashi, Kazumasa, Mizuno, Kensaku
Formato: Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2954123/
https://www.ncbi.nlm.nih.gov/pubmed/20810787
http://dx.doi.org/10.1091/mbc.E10-02-0095