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Thermal Stability of the Human Immunodeficiency Virus Type 1 (HIV-1) Receptors, CD4 and CXCR4, Reconstituted in Proteoliposomes

BACKGROUND: The entry of human immunodeficiency virus (HIV-1) into host cells involves the interaction of the viral exterior envelope glycoprotein, gp120, and receptors on the target cell. The HIV-1 receptors are CD4 and one of two chemokine receptors, CCR5 or CXCR4. METHODOLOGY/PRINCIPAL FINDINGS:...

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Detalles Bibliográficos
Autores principales: Zhukovsky, Mikhail A., Basmaciogullari, Stéphane, Pacheco, Beatriz, Wang, Liping, Madani, Navid, Haim, Hillel, Sodroski, Joseph
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2954141/
https://www.ncbi.nlm.nih.gov/pubmed/20967243
http://dx.doi.org/10.1371/journal.pone.0013249