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Increased Immune Complexes of Hypocretin Autoantibodies in Narcolepsy

BACKGROUND: Hypocretin peptides participate in the regulation of sleep-wake cycle while deficiency in hypocretin signaling and loss of hypocretin neurons are causative for narcolepsy-cataplexy. However, the mechanism responsible for alteration of the hypocretin system in narcolepsy-cataplexy and its...

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Detalles Bibliográficos
Autores principales: Deloumeau, Aude, Bayard, Sophie, Coquerel, Quentin, Déchelotte, Pierre, Bole-Feysot, Christine, Carlander, Bertrand, Cochen De Cock, Valérie, Fetissov, Sergueï O., Dauvilliers, Yves
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2954157/
https://www.ncbi.nlm.nih.gov/pubmed/20967199
http://dx.doi.org/10.1371/journal.pone.0013320