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Bile Acid-Induced Virulence Gene Expression of Vibrio parahaemolyticus Reveals a Novel Therapeutic Potential for Bile Acid Sequestrants

Vibrio parahaemolyticus, a bacterial pathogen, causes human gastroenteritis. A type III secretion system (T3SS2) encoded in pathogenicity island (Vp-PAI) is the main contributor to enterotoxicity and expression of Vp-PAI encoded genes is regulated by two transcriptional regulators, VtrA and VtrB. Ho...

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Detalles Bibliográficos
Autores principales: Gotoh, Kazuyoshi, Kodama, Toshio, Hiyoshi, Hirotaka, Izutsu, Kaori, Park, Kwon-Sam, Dryselius, Rikard, Akeda, Yukihiro, Honda, Takeshi, Iida, Tetsuya
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2954181/
https://www.ncbi.nlm.nih.gov/pubmed/20967223
http://dx.doi.org/10.1371/journal.pone.0013365