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Inhibition of the Liver Enriched Protein FOXA2 Recovers HNF6 Activity in Human Colon Carcinoma and Liver Hepatoma Cells

Recently, we demonstrated that the transcription factors HNF6 and FOXA2 function as key regulators in human colorectal liver metastases. To better understand their proposed inhibitory crosstalk, the consequences of functional knockdown of FOXA2 on HNF6 and C/EBPα activity were investigated in the hu...

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Detalles Bibliográficos
Autores principales: Lehner, Frank, Kulik, Ulf, Klempnauer, Juergen, Borlak, Juergen
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2954183/
https://www.ncbi.nlm.nih.gov/pubmed/20967225
http://dx.doi.org/10.1371/journal.pone.0013344