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DUFs: families in search of function

Domains of unknown function (DUFs) are a large set of uncharacterized protein families that are found in the Pfam database. Here, the scale and growth of functionally uncharacterized families in biological databases are surveyed and the prospects for discovering their function are examined. In parti...

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Detalles Bibliográficos
Autores principales: Bateman, Alex, Coggill, Penny, Finn, Robert D.
Formato: Texto
Lenguaje:English
Publicado: International Union of Crystallography 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2954198/
https://www.ncbi.nlm.nih.gov/pubmed/20944204
http://dx.doi.org/10.1107/S1744309110001685