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Activation of ASK1, downstream MAPKK and MAPK isoforms during cardiac ischaemia

p38 MAPK is activated potently during cardiac ischaemia, although the precise mechanism by which it is activated is unclear. We used the isolated perfused rat heart to investigate the signalling pathways activated upstream of p38 during global cardiac ischaemia. Ischaemia strongly activated p38α but...

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Detalles Bibliográficos
Autores principales: Harding, Stephen J., Browne, Gareth J., Miller, Bryan W., Prigent, Sally A., Dickens, Martin
Formato: Texto
Lenguaje:English
Publicado: Elsevier Pub. Co 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2954285/
https://www.ncbi.nlm.nih.gov/pubmed/20550965
http://dx.doi.org/10.1016/j.bbadis.2010.06.005