In vitro and in vivo pharmacological profile of the 5-benzyl analogue of 14-methoxymetopon, a novel μ opioid analgesic with reduced propensity to alter motor function

Opioids are the most effective analgesics for pain management, and efficient pain control is a therapeutic priority. Herein, we describe the synthesis and pharmacological activities of the 5-benzyl analogue of the μ opioid analgesic 14-methoxymetopon (14-MM). The result of the replacement of the 5-m...

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Detalles Bibliográficos
Autores principales: Spetea, Mariana, Bohotin, Catalina R., Asim, Muhammad F., Stübegger, Kurt, Schmidhammer, Helmut
Formato: Texto
Lenguaje:English
Publicado: Elsevier Science B.V 2010
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2954314/
https://www.ncbi.nlm.nih.gov/pubmed/20600882
http://dx.doi.org/10.1016/j.ejps.2010.05.018

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2954314/
https://www.ncbi.nlm.nih.gov/pubmed/20600882
http://dx.doi.org/10.1016/j.ejps.2010.05.018

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