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Tracing the Derivation of Embryonic Stem Cells from the Inner Cell Mass by Single-Cell RNA-Seq Analysis

During the transition from the inner cell mass (ICM) cells of blastocysts to pluripotent embryonic stem cells (ESCs) in vitro, a normal developmental program is replaced in cells that acquire a capacity for infinite self-renewal and pluripotency. We explored the underlying mechanism of this switch b...

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Detalles Bibliográficos
Autores principales: Tang, Fuchou, Barbacioru, Catalin, Bao, Siqin, Lee, Caroline, Nordman, Ellen, Wang, Xiaohui, Lao, Kaiqin, Surani, M. Azim
Formato: Texto
Lenguaje:English
Publicado: Cell Press 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2954317/
https://www.ncbi.nlm.nih.gov/pubmed/20452321
http://dx.doi.org/10.1016/j.stem.2010.03.015