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New structure enlivens interest in P2X receptors

P2X receptors are ATP-gated membrane ion channels with multifarious roles, including afferent sensation, autocrine feedback loops, and inflammation. Their molecular operation has been less well elucidated compared with other ligand-gated channels (nicotinic acetylcholine receptors, ionotropic glutam...

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Detalles Bibliográficos
Autores principales: Browne, Liam E., Jiang, Lin-Hua, North, R. Alan
Formato: Texto
Lenguaje:English
Publicado: Published By Elsevier In Association With The International Union Of Pharmacology 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2954318/
https://www.ncbi.nlm.nih.gov/pubmed/20227116
http://dx.doi.org/10.1016/j.tips.2010.02.004