Normal passive viscoelasticity but abnormal myofibrillar force generation in human hypertrophic cardiomyopathy

Hypertrophic cardiomyopathy (HCM) is characterized by left ventricular hypertrophy, increased ventricular stiffness and impaired diastolic filling. We investigated to what extent myocardial functional defects can be explained by alterations in the passive and active properties of human cardiac myofi...

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Detalles Bibliográficos
Autores principales: Hoskins, Anita C., Jacques, Adam, Bardswell, Sonya C., McKenna, William J., Tsang, Victor, dos Remedios, Cristobal G., Ehler, Elisabeth, Adams, Kim, Jalilzadeh, Shapour, Avkiran, Metin, Watkins, Hugh, Redwood, Charles, Marston, Steven B., Kentish, Jonathan C.
Formato: Texto
Lenguaje:English
Publicado: Academic Press 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2954357/
https://www.ncbi.nlm.nih.gov/pubmed/20615414
http://dx.doi.org/10.1016/j.yjmcc.2010.06.006