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Normal passive viscoelasticity but abnormal myofibrillar force generation in human hypertrophic cardiomyopathy
Hypertrophic cardiomyopathy (HCM) is characterized by left ventricular hypertrophy, increased ventricular stiffness and impaired diastolic filling. We investigated to what extent myocardial functional defects can be explained by alterations in the passive and active properties of human cardiac myofi...
Autores principales: | Hoskins, Anita C., Jacques, Adam, Bardswell, Sonya C., McKenna, William J., Tsang, Victor, dos Remedios, Cristobal G., Ehler, Elisabeth, Adams, Kim, Jalilzadeh, Shapour, Avkiran, Metin, Watkins, Hugh, Redwood, Charles, Marston, Steven B., Kentish, Jonathan C. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Academic Press
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2954357/ https://www.ncbi.nlm.nih.gov/pubmed/20615414 http://dx.doi.org/10.1016/j.yjmcc.2010.06.006 |
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