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Bistability in Apoptosis by Receptor Clustering

Apoptosis is a highly regulated cell death mechanism involved in many physiological processes. A key component of extrinsically activated apoptosis is the death receptor Fas which, on binding to its cognate ligand FasL, oligomerize to form the death-inducing signaling complex. Motivated by recent ex...

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Detalles Bibliográficos
Autores principales: Ho, Kenneth L., Harrington, Heather A.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2954819/
https://www.ncbi.nlm.nih.gov/pubmed/20976242
http://dx.doi.org/10.1371/journal.pcbi.1000956