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Use of a highly sensitive strand-specific quantitative PCR to identify abortive replication in the mouse model of respiratory syncytial virus disease

BACKGROUND: The BALB/c mouse is commonly used to study RSV infection and disease. However, despite the many advantages of this well-characterised model, the inoculum is large, viral replication is restricted and only a very small amount of virus can be recovered from infected animals. A key question...

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Detalles Bibliográficos
Autores principales: Bannister, Richard, Rodrigues, Deborah, Murray, Edward J, Laxton, Carl, Westby, Mike, Bright, Helen
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2954858/
https://www.ncbi.nlm.nih.gov/pubmed/20860795
http://dx.doi.org/10.1186/1743-422X-7-250