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Use of a highly sensitive strand-specific quantitative PCR to identify abortive replication in the mouse model of respiratory syncytial virus disease
BACKGROUND: The BALB/c mouse is commonly used to study RSV infection and disease. However, despite the many advantages of this well-characterised model, the inoculum is large, viral replication is restricted and only a very small amount of virus can be recovered from infected animals. A key question...
Autores principales: | Bannister, Richard, Rodrigues, Deborah, Murray, Edward J, Laxton, Carl, Westby, Mike, Bright, Helen |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2954858/ https://www.ncbi.nlm.nih.gov/pubmed/20860795 http://dx.doi.org/10.1186/1743-422X-7-250 |
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