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Integrin α2-deficient mice provide insights into specific functions of collagen receptors in the kidney

BACKGROUND: Integrins are important cellular receptors for collagens. Within the glomerulus, podocytes regulate the integrity of the glomerular basement membrane (GBM) by sensing the presence of collagen and regulating collagen IV synthesis. The present study evaluates the role of integrin α2 (ITGA2...

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Detalles Bibliográficos
Autores principales: Girgert, Rainer, Martin, Maria, Kruegel, Jenny, Miosge, Nicolai, Temme, Johanna, Eckes, Beate, Müller, Gerhard-Anton, Gross, Oliver
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2954872/
https://www.ncbi.nlm.nih.gov/pubmed/20860797
http://dx.doi.org/10.1186/1755-1536-3-19