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Integrin α2-deficient mice provide insights into specific functions of collagen receptors in the kidney
BACKGROUND: Integrins are important cellular receptors for collagens. Within the glomerulus, podocytes regulate the integrity of the glomerular basement membrane (GBM) by sensing the presence of collagen and regulating collagen IV synthesis. The present study evaluates the role of integrin α2 (ITGA2...
Autores principales: | , , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2954872/ https://www.ncbi.nlm.nih.gov/pubmed/20860797 http://dx.doi.org/10.1186/1755-1536-3-19 |