β-Actin and γ-Actin Are Each Dispensable for Auditory Hair Cell Development But Required for Stereocilia Maintenance

Hair cell stereocilia structure depends on actin filaments composed of cytoplasmic β-actin and γ-actin isoforms. Mutations in either gene can lead to progressive hearing loss in humans. Since β-actin and γ-actin isoforms are 99% identical at the protein level, it is unclear whether each isoform has...

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Detalles Bibliográficos
Autores principales: Perrin, Benjamin J., Sonnemann, Kevin J., Ervasti, James M.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2954897/
https://www.ncbi.nlm.nih.gov/pubmed/20976199
http://dx.doi.org/10.1371/journal.pgen.1001158

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2954897/
https://www.ncbi.nlm.nih.gov/pubmed/20976199
http://dx.doi.org/10.1371/journal.pgen.1001158

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