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Polymorphisms of genes coding for ghrelin and its receptor in relation to colorectal cancer risk: a two-step gene-wide case-control study

BACKGROUND: Ghrelin, an endogenous ligand for the growth hormone secretagogue receptor (GHSR), has two major functions: the stimulation of the growth hormone production and the stimulation of food intake. Accumulating evidence also indicates a role of ghrelin in cancer development. METHODS: We condu...

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Detalles Bibliográficos
Autores principales: Campa, Daniele, Pardini, Barbara, Naccarati, Alessio, Vodickova, Ludmila, Novotny, Jan, Steinke, Verena, Rahner, Nils, Holinski-Feder, Elke, Morak, Monika, Schackert, Hans K, Görgens, Heike, Kötting, Judith, Betz, Beate, Kloor, Matthias, Engel, Christoph, Büttner, Reinhard, Propping, Peter, Försti, Asta, Hemminki, Kari, Barale, Roberto, Vodicka, Pavel, Canzian, Federico
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2954942/
https://www.ncbi.nlm.nih.gov/pubmed/20920174
http://dx.doi.org/10.1186/1471-230X-10-112