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Expression of glypican 3 in placental site trophoblastic tumor

BACKGROUND: Glypican-3 (GPC3) is a membrane-bound heparan sulfate proteoglycan that functions in embryonic cell growth and differentiation and is highly expressed in the placenta. GPC3 is mutated in Simpson-Golabi-Behmel syndrome, which is characterized by tissue overgrowth and an increased risk of...

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Detalles Bibliográficos
Autores principales: Ou-Yang, Robin J, Hui, Pei, Yang, Ximing J, Zynger, Debra L
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2954974/
https://www.ncbi.nlm.nih.gov/pubmed/20868507
http://dx.doi.org/10.1186/1746-1596-5-64