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Molecular evolution and the role of oxidative stress in the expansion and functional diversification of cytosolic glutathione transferases
BACKGROUND: Cytosolic glutathione transferases (cGST) are a large group of ubiquitous enzymes involved in detoxification and are well known for their undesired side effects during chemotherapy. In this work we have performed thorough phylogenetic analyses to understand the various aspects of the evo...
Autores principales: | da Fonseca, Rute R, Johnson, Warren E, O'Brien, Stephen J, Vasconcelos, Vítor, Antunes, Agostinho |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2955027/ https://www.ncbi.nlm.nih.gov/pubmed/20843339 http://dx.doi.org/10.1186/1471-2148-10-281 |
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