Phase I clinical and pharmacokinetic study of sorafenib in combination with carboplatin and paclitaxel in patients with advanced non–small cell lung cancer

Objectives Unsatisfactory efficacy of current treatments for advanced lung cancer has prompted the search for new therapies, with sorafenib, a multikinase inhibitor, being one candidate drug. This phase I trial was conducted to evaluate drug safety and pharmacokinetics as well as tumor response of s...

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Detalles Bibliográficos
Autores principales: Okamoto, Isamu, Miyazaki, Masaki, Morinaga, Ryotaro, Kaneda, Hiroyasu, Ueda, Shinya, Hasegawa, Yoshikazu, Satoh, Taroh, Kawada, Akira, Fukuoka, Masahiro, Fukino, Koichi, Tanigawa, Takahiko, Nakagawa, Kazuhiko
Formato: Texto
Lenguaje:English
Publicado: Springer US 2009
Materias:
Phase I Studies
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2955234/
https://www.ncbi.nlm.nih.gov/pubmed/19760364
http://dx.doi.org/10.1007/s10637-009-9321-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2955234/
https://www.ncbi.nlm.nih.gov/pubmed/19760364
http://dx.doi.org/10.1007/s10637-009-9321-x

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