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Prothrombin complex concentrate mitigates diffuse bleeding after cardiopulmonary bypass in a porcine model

BACKGROUND: Extracorporeal circuit priming and intravascular volume expansion during cardiopulmonary bypass (CPB) may lead to dilutional coagulopathy and excessive diffuse postoperative bleeding. Prothrombin complex concentrate (PCC) containing clotting factors II (FII), VII (FVII), IX (FIX), and X...

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Detalles Bibliográficos
Autores principales: Kaspereit, F., Hoffmann, S., Pragst, I., Dickneite, G.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2955534/
https://www.ncbi.nlm.nih.gov/pubmed/20716565
http://dx.doi.org/10.1093/bja/aeq216