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Prothrombin complex concentrate mitigates diffuse bleeding after cardiopulmonary bypass in a porcine model
BACKGROUND: Extracorporeal circuit priming and intravascular volume expansion during cardiopulmonary bypass (CPB) may lead to dilutional coagulopathy and excessive diffuse postoperative bleeding. Prothrombin complex concentrate (PCC) containing clotting factors II (FII), VII (FVII), IX (FIX), and X...
Autores principales: | , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2955534/ https://www.ncbi.nlm.nih.gov/pubmed/20716565 http://dx.doi.org/10.1093/bja/aeq216 |