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Transgenic Expression of P1A Induced Thymic Tumor: A Role for Onco-Fetal Antigens in Tumorigenesis

P1A is the first known tumor rejection antigen. It is expressed in embryonic stem cells and multiple tumors but is silent in adult tissues except for the testis and placenta. Therefore, P1A represents a prototype for onco-fetal antigens. To test the potential function of P1A in tumorigenesis, we use...

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Detalles Bibliográficos
Autores principales: Li, Chi-Shan, Chen, Chong, Zheng, Pan, Liu, Yang
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2955541/
https://www.ncbi.nlm.nih.gov/pubmed/20976169
http://dx.doi.org/10.1371/journal.pone.0013439