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Bioreducible Liposomes for Gene Delivery: From the Formulation to the Mechanism of Action

BACKGROUND: A promising strategy to create stimuli-responsive gene delivery systems is to exploit the redox gradient between the oxidizing extracellular milieu and the reducing cytoplasm in order to disassemble DNA/cationic lipid complexes (lipoplexes). On these premises, we previously described the...

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Detalles Bibliográficos
Autores principales: Candiani, Gabriele, Pezzoli, Daniele, Ciani, Laura, Chiesa, Roberto, Ristori, Sandra
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2955545/
https://www.ncbi.nlm.nih.gov/pubmed/20976172
http://dx.doi.org/10.1371/journal.pone.0013430