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Bioreducible Liposomes for Gene Delivery: From the Formulation to the Mechanism of Action
BACKGROUND: A promising strategy to create stimuli-responsive gene delivery systems is to exploit the redox gradient between the oxidizing extracellular milieu and the reducing cytoplasm in order to disassemble DNA/cationic lipid complexes (lipoplexes). On these premises, we previously described the...
| Autores principales: | , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2010
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2955545/ https://www.ncbi.nlm.nih.gov/pubmed/20976172 http://dx.doi.org/10.1371/journal.pone.0013430 |