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The Lack of ADAM17 Activity during Embryonic Development Causes Hemorrhage and Impairs Vessel Formation
BACKGROUND: ADAM17/TACE activity is important during embryonic development. We wished to investigate possible roles of this metalloprotease, focusing on vascular development. METHODOLOGY/PRINCIPAL FINDINGS: Mice mutant in the enzymatic activity of ADAM17 were examined at various stages of embryonic...
| Autores principales: | , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2010
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2955552/ https://www.ncbi.nlm.nih.gov/pubmed/20976179 http://dx.doi.org/10.1371/journal.pone.0013433 |