Beta-arrestin inhibits CAMKKbeta-dependent AMPK activation downstream of protease-activated-receptor-2

BACKGROUND: Proteinase-activated-receptor-2 (PAR(2)) is a seven transmembrane receptor that can activate two separate signaling arms: one through Gαq and Ca(2+ )mobilization, and a second through recruitment of β-arrestin scaffolds. In some cases downstream targets of the Gαq/Ca(2+ )signaling arm ar...

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Detalles Bibliográficos
Autores principales: Wang, Ping, Jiang, Yong, Wang, Yinsheng, Shyy, John Y, DeFea, Kathryn A
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2955585/
https://www.ncbi.nlm.nih.gov/pubmed/20858278
http://dx.doi.org/10.1186/1471-2091-11-36

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2955585/
https://www.ncbi.nlm.nih.gov/pubmed/20858278
http://dx.doi.org/10.1186/1471-2091-11-36

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