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Epigenetic regulation of CD44 in Hodgkin and non-Hodgkin lymphoma

BACKGROUND: Epigenetic inactivation of tumor suppressor genes (TSG) by promoter CpG island hypermethylation is a hallmark of cancer. To assay its extent in human lymphoma, methylation of 24 TSG was analyzed in lymphoma-derived cell lines as well as in patient samples. METHODS: We screened for TSG me...

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Detalles Bibliográficos
Autores principales: Eberth, Sonja, Schneider, Björn, Rosenwald, Andreas, Hartmann, Elena M, Romani, Julia, Zaborski, Margarete, Siebert, Reiner, Drexler, Hans G, Quentmeier, Hilmar
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2955612/
https://www.ncbi.nlm.nih.gov/pubmed/20920234
http://dx.doi.org/10.1186/1471-2407-10-517