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Malignant transformation in a defined genetic background: proteome changes displayed by 2D-PAGE

BACKGROUND: Cancer arises from normal cells through the stepwise accumulation of genetic alterations. Cancer development can be studied by direct genetic manipulation within experimental models of tumorigenesis. Thereby, confusion by the genetic heterogeneity of patients can be circumvented. Moreove...

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Detalles Bibliográficos
Autores principales: Pütz, Stephanie M, Vogiatzi, Fotini, Stiewe, Thorsten, Sickmann, Albert
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2955615/
https://www.ncbi.nlm.nih.gov/pubmed/20860785
http://dx.doi.org/10.1186/1476-4598-9-254