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Malignant transformation in a defined genetic background: proteome changes displayed by 2D-PAGE
BACKGROUND: Cancer arises from normal cells through the stepwise accumulation of genetic alterations. Cancer development can be studied by direct genetic manipulation within experimental models of tumorigenesis. Thereby, confusion by the genetic heterogeneity of patients can be circumvented. Moreove...
| Autores principales: | , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2010
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2955615/ https://www.ncbi.nlm.nih.gov/pubmed/20860785 http://dx.doi.org/10.1186/1476-4598-9-254 |